Established in 2009, we are at the forefront of nurse-led implementation research and have been successful in obtaining multiple Category 1 research grants (National Health and Medical Research Council, Australian Research Council), as well as other national and international funding.

In partnership with clinical, policy, and academic partners, we specialise in implementation science research examining ways to promote evidence translation in the areas of stroke management, hospital-acquired complications, and de-implementation of low value nursing care. We collaborate with world-class national and international researchers and policy makers including: Agency for Clinical Innovation, Clinical Excellence Commission, Australian Commission on Safety and Quality in Health Care, and the Stroke Foundation.

Current NRI projects listed by National Safety and Quality Health Service Standards

NRI researchers currently collaborate on 29 research projects. Nine led by NRI researchers* with the remaining projects as co-investigators. Twelve projects^ involve collaboration with our St Vincent's Health Australia partners.

  1. ACCELERATE Trial: Assessment and CommuniCation ExcelLEnce foR sAfe paTient outcomEs*^ (Also Standard 5, 6 and 8)
  2. ACCELERATE Plus Trial: Assessment and CommuniCation ExcelLEnce foR sAfe paTient outcomEs*^ (Also Standard 5, 6 and 8)
  3. Centre of Research Excellence in Wiser Wound Care: Improving evidence-based pressure injury prevention^ (Also Standard 5)
  4. The Stroke Golden Hour: delivering urgent stroke care to Australians (Also Standard 5)

5. AVERT-DOSE (Determining Optimal early rehabilitation after StrokE): A multi-arm covariate-adjusted, response adaptive randomised controlled trial^
6. Centre for Research Excellence in Paediatric Emergency Medicine
7. Centre for Research Excellence to Accelerate Stroke Trial Innovation and Translation
8. Centre for Research Excellence - Frailty ADD: Improving Hospital Outcomes for Frail Patients Across Different Disciplines (Frailty-ADD CRE)^
9. Digital solutions for heart failure best practice care
10. Frailty response in aortic stenosis patients undergoing transcatheter aortic valve implantation: A pilot, cluster randomised trial (FRAIL-AS Response Trial)*^
11. From theory to practice: Unveiling the theoretical basis and components of effective implementation strategies for improving nursing practice and patient outcomes
12. Improving the health system's response when patients are harmed: a mixed-methods study
13. P-OMICS-flow grant [Precision Medicine Clinic]
14. Quality in Acute Stroke Care (QASC) Australasia Project*^
15. Quality in Acute Stroke Care (QASC) Europe Project*^
16. REducing cardioVascular and kidnEy RiSk in people with diabEtes (the REVERSE study)
17. Regional And Rural Research Translation in Bronchiolitis (RARRT-Bronch)
18. Transforming acute hospital care to improve outcomes for stroke*
19. Understanding Reception of Care Technology for Healthy Ageing at Home*
20. Frailty on the frontline: Evaluating the impact and integration of a frailty clinical champion in Australian and Swedish cardiovascular programs

21. Improving End-of-Life communication in Australian hospitals for patient safety and care
22. Improving End-of-Life Care in Australian cardiology wards: A retrospectivae medical record audit
23. Patient Acceptability of Nurse-Led Physical Assessments and Structured Bedside Handovers (The ACCELERATE Plus: Acceptability Study)*^

24. Giving the AllClear - stopping breast cancer relapse and death^
25. The PREPARE Study: Improving the PREPAREdness of family members for end-of-life care in the intensive care unit*^

26. Centre of Research Excellence for effective and sustained health system implementation
27. National Health and Medical Research Council (NHMRC) - 2025-26 Supporting Research Translation Centres Grant^
28. ReCITE: Remote Constraint Induced Therapy of the upper Extremity - An implementation study*
29. Understanding Reception of Care Technology for Healthy Ageing at Home

Featured projects

SPHERE Nursing & Midwifery Clinician Researcher Pathway

A 12-year progressive training and career pathway from internships to graduate education.

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Quality in Acute Stroke Care Research Program

The Quality in Acute Stroke Care (QASC) research program comprises the research projects outlining the effectiveness and supported implementation of the Fever, Sugar, Swallow (FeSS) Protocols following stroke.

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The FRAIL-AS Response Trial

The Frailty Response in Patients with Aortic Stenosis undergoing Transcatheter Aortic Valve Implantation: a pilot, cluster-randomised controlled trial

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Wound Care Research Projects

The NHMRC Centre of Research Excellence (CRE) in Wiser Wound Care aims to improve the delivery of wound care in hospitals by generating high-quality research evidence in collaboration with consumers and clinicians.

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The ACCELERATE Trial

The Assessment and CommuniCation ExcelLEnce foR sAfe paTient outcomEs Trial to assess the effect of improving patient assessment and clinical handover on patient adverse events.

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The ACCELERATE Plus Trial

The Assessment and CommuniCation ExcelLEnce foR sAfe paTient outcomEs Plus (ACCELERATE Plus) randomised control trial builds upon our previous ACCELERATE feasibility Trial.

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