The Advanced cancer & Cachexia Exercise Trial
Published September 5, 2018
Cachexia is a syndrome characterised by involuntary body weight or muscle mass loss. Cachexia is a known risk for individuals with cancer and up to 80% of patients with advanced cancer may develop cachexia. Cachexia imposes a significant burden on patients as body weight or muscle mass loss is associated with reduced physical function, worse cancer treatment side effects and cancer symptoms, poorer patient quality of life and shorter survival. Currently, there is no single pharmaceutical or nutritional intervention that can fully prevent or reverse cancer cachexia.
Emerging research suggests exercise may slow the progression of cachexia as well as manage its adverse effects, including patient reported symptoms. There is also a plethora of evidence showing exercise is an effective strategy to maintain physical fitness, including muscle mass and strength, and improve patient health-related quality of life in adults with a diagnosis of cancer. This study will therefore aim to evaluate the feasibility and effectiveness of exercise as a management strategy to counteract the burden of cachexia in patients with advanced cancer.
Who is this trial for?
What does participation involve?
Where are the exercise clinics?
How do I get involved?