Project team: Professor Christine Imms, Dr Brooke Adair, Dr Melinda Randall, Professor Dinah Reddihough (Murdoch Childrens Research Institute), Professor Rob Carter (Deakin University), Dr Brian Hoare (Monash Health), Dr Susan Greaves (Royal Childrens Hospital), Dr Margaret Wallen (Cerebral Palsy Association), Associate Professor Catherine Elliott (Curtin University), Dr Elizabeth Bradshaw, Ms Sophy Shi (Deakin University), Ms Francesca Orsini (Murdoch Childrens Research Institute), and doctoral students: Mr Simon Garbellini, Ms Corrin Walmsley.
These concurrently run randomised controlled trials aim to assess whether the provision of a serially adjusted wrist/hand orthosis (WHO), in combination with usual multi-disciplinary care, prevents or reduces muscle contracture/stiffness. Secondary analyses will focus on the impact of WHO provision on pain, activity performance, participation and quality of life. A cost benefit analyses of the intervention will also be performed. Eligible participants are children with cerebral palsy; the iWHOTrial focuses on young children less than 24 months at study enrolment and the MITrial will assess WHO provision for children ages 5 to 15 years. The effect of the WHO will be monitored over a 3 year period, with assessments occurring every 6 months. Throughout the projects three novel measurement devices will also be designed, tested and validated for use with this population. The results will inform us as to whether rigid WHOs are needed, or if activity-based therapy alone is sufficient to prevent or reduce the development of musculo-skeletal impairments in children with cerebral palsy. Published evidence from the trial will inform families, practitioners and policy makers regarding clinical and cost effectiveness of WHO to reduce impairment and promote activity and participation in young children with cerebral palsy.
This project is embedded within the NHMRC funded Centre for Research Excellence – Cerebral Palsy. Both trials are registered on the Australian and New Zealand Trials Registry.
Sample wrist hand orthosis